Phenibut

full agonist of the GABAB receptor
between 30- and 68-fold lower affinity for the GABAB receptor than baclofen
(R)-Phenibut has more than 100-fold higher affinity for the GABAB receptor than does (S)-phenibut
binds to and blocks α2δ subunit-containing VDCCs, similarly to gabapentin and pregabalin, and hence is a gabapentinoid
reported to be well-absorbed
It distributes widely throughout the body and across the blood–brain barrier.
Phenibut can be used recreationally due to its ability to produce euphoria, anxiolysis, and increased sociability