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Paraxanthine

- Psychoactive CNS stimulant
- Antagonism of Adenosine Receptors
- Paraxanthine adenosine receptor binding affinity
- 21 μM for A1
- 32 μM for A2A
- 4.5 μM for A2B
- >100 for μM for A3
- Selective Inhibitor of cGMP-preferring Phosphodiesterase (PDE9) activity
- Inhibits TNF-alpha Synthesis
- Inhibits Leukotriene Synthesis
- Reduces Inflammation
- Reduces Innate Immunity