r/anhedonia
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HHC

Condition Onset of Effects Bioavailability Likely Mechanism Empty Stomach Faster (e.g., 1.5 hours) Lower (e.g., ~6% for CBD) Quick absorption, limited fat for solubility Full Stomach Delayed (e.g., 5-10 hours) Higher (potentially 4x, e.g., ~24% for CBD) Enhanced by fats, lymphatic uptake, delayed gastric emptying