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CBD

- Low affinity for, and acts as a negative allosteric modulator of the CB1 cannabinoid receptor.
- May be an antagonist of GPR55.
- May interact with various neurotransmitters, such as serotonin, dopamine, and GABA.
- In humans, oral bioavailability is
- Approximately 6% in fasting state
- Approximately 36.5-57.3% in fed-state